Damage to the vegetative nervous system is common during Parkinson’s disease. The main symptoms include constipation, blood pressure fluctuations (sometimes hypotension in the late morning and vesperal hypertension) and urinary disorders with foremost foremost overactive bladder with pollakiuria (frequent urge to urinate) and nocturia (nocturnal urge to urinate). Some of these symptoms, especially urinary symptoms, can be inaugural of the disease and precede motor signs as well as tremors. The management of these different symptoms is sometimes complex, particularly with regard to concerns blood pressure fluctuations and requires adapting other therapies (possible decrease in anti-hypertensive treatment in the morning). With regard to overactive bladder, in addition to non-drug treatments without side effects, treatment with neurostimulation of the tibial nerve in the ankle can be proposed (UROSTIM) and be effective with good tolerance.